March 2011: New Data Show that Coffee Consumption May Reduce Total Cancer Incidence

A new meta-analysis published in BioMed Central Cancer suggests that coffee consumption may reduce total cancer incidence.1 Xiofeng Yu et al‘s analysis of 59 studies also showed that coffee consumption may be inversely associatedwith the risk of bladder, breast, buccal cavity, pharynx, colorectum, endometrium, oesophagus, hepatocellular, leukemia, pancreas and prostate cancers.

This analysis of 59 studies included 40 prospective cohort studies and 2,179,126 participants.

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “This study adds to the growing scientific data that suggests moderate coffee consumption, 4 – 5 cups of coffee per day, is not associated with an increased risk of cancer. It is particularly encouraging to see that this meta-analysis also suggests that coffee consumption may be inversely associated with cancer at a range of sites in the body. This study builds on the World Cancer Fund’s advice that coffee has no significant relationship with the risk of cancer at any site 2 .

As advised by the NHS, pregnant women should moderate their intake of caffeine to 200mg per day from all sources.3

References

1. Yu, X. et al. Coffee consumption and risk of cancers: a meta-analysis of cohort studies. BMC Cancer 2011, 11:96. Doi:10.1186/1471-2407-11-96

2. Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective as well as the companion report, Policy and Action for Cancer Prevention , available online: www.dietandcancerreport.org

3. NHS Choices, http://www.nhs.uk/Planners/pregnancycareplanner/pages/Healthinpregnancyhome.aspx

May 2011: New Data Suggest that Moderate Coffee Consumption is Not Associated with CVD or All-Cause Mortality in Women

Research published in the American Journal of Clinical Nutritionshows that moderate coffee consumption is not associated with cardiovascular disease (CVD) associated morality or all-cause mortality.1The investigators followed a cohort of 11,697 women and found there to be no association between the consumption of filtered caffeinated coffee and the risk of all-cause or CVD mortality.1

These data build on research in the area of cardiovascular health which has shown that long-term coffee consumption does not increase the risk of coronary heart disease2, stroke3, and premature death from CVD or all-causes.4

This research is important as:

· Heart and circulatory disease is the UK’s biggest killer5

· More than one in five deaths in women before the age of 75 is due to CVD5

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “These data add to the overwhelming weight of scientific research which demonstrates that moderate coffee consumption of 4-5 cups per day is safe and may be associated with some health benefits. This research also builds further on the British Heart Foundation’s advice that moderate amounts of caffeine (four to five cups per day) does not lead to arrhythmias, coronary heart disease, or effect an individual’s blood pressure, and nor does it increase the risk.6

As advised by the NHS, pregnant women should moderate their intake of caffeine to 200mg per day from all sources.7If you would like to speak with a healthcare professional or a representative from the British Coffee Association to gain further information please contact Lottie Tupholme on 020 8392 6937 at Red Door Communications.

References

1. Lopez-Garcia E, Rodriguez-Artalejo F, et al. Coffee consumption and mortality in women with cardiovascular disease. Am J Clin Nutr. doi: 10.3945/ajcn.110.010249

2. Lopez-Garcia E, van Dam RM, Willett WC, et al. Coffee consumption and coronary heart disease in men and women: a prospective cohort study. Circulation 2006;113:2045–53

3. Lopez-Garcia E, Rodriguez-Artalejo F, Rexrode KM, Logroscino G, Hu FB, van Dam RM. Coffee consumption and risk of stroke in women. Circulation 2009;119:1116–23

4. Lopez-Garcia E, van Dam RM, Li TY, Rodriguez-Artalejo F, Hu FB. The relationship of coffee consumption with mortality. Ann Intern Med. 2008;148:904–14

5. Coronary Heart Disease Statistics 2010. British Heart Foundation

6. The British Heart Foundation. http://www.bhf.org.uk/publications/view-publication.aspx?ps=1000767

7. NHS Choices, http://www.nhs.uk/Planners/pregnancycareplanner/pages/Healthinpregnancyhome.aspx

May 2011: New Data Suggest that Moderate Coffee Consumption May be Associated with a Reduced Risk of Venous Thromboembolism (VTE)

Research published in the Journal of Thrombosis and Haemostasis shows that moderate coffee consumption may be associated with a reduced risk of venous thromboembolism (VTE) in the general population.1 Analysis of 26,755 subjects showed that a daily coffee consumption of 5-6 cups of coffee was significantly associated with a 33% reduced risk of VTE compared to those who didn’t drink coffee.1

This research is important as:

· VTE is a major health problem – each year, more people are affected by VTE than breast cancer, lung cancer and AIDS2

· It is estimated that approximately 50% of people who have a DVT will go on to develop a pulmonary embolism (PE), PE is the single, most common preventable cause of death in hospital patients2

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “These data add to the overwhelming weight of scientific research which demonstrates that moderate coffee consumption of 4-5 cups per day is safe and may be associated with some health benefits. This research is encouraging as it suggests that moderate coffee consumption may be associated with a reduced risk of VTE, however more studies are required to understand the relationship further.”

As advised by the NHS, pregnant women should moderate their intake of caffeine to 200mg per day from all sources.3

References

1. Enga, K, et al. Coffee consumption and the Risk of Venous Thromboembolism – the Tromsø study. Journal of Thrombosis and Haemostasis. doi: 10.1111/j.1538-7836.2011.04353.x

2. Lifeblood, The Thrombosis Charity: http://www.thrombosis-charity.org.uk/cms/index.php?option=com_content&task=view&id=287&Itemid=374

3. NHS Choices, http://www.nhs.uk/Planners/pregnancycareplanner/pages/Healthinpregnancyhome.aspx

April 2011: New Data Suggests that Moderate Coffee Consumption is Well Tolerated in Most Patients with Known or Suspected Arrhythmia

Research published in the American Journal of Medicine shows that moderate coffee consumption is well tolerated in patients with either known or suspected arrhythmia.1The investigators reviewed evidence relating to caffeine and arrhythmia in order to provide recommendations for patients experiencing arrthymia.

These data build on the British Heart Foundation’s advice that moderate amounts of caffeine (four to five cups per day) does not lead to arrhythmias, coronary heart disease, or effect an individual’s blood pressure, and nor does it increase the risk2

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “These data add to the overwhelming weight of scientific research which demonstrates that moderate coffee consumption of 4-5 cups per day is safe and may be associated with some health benefits. This research demonstrates that moderate coffee consumption is well tolerated by patients with arrhythmia and these results are encouraging.”

As advised by the NHS, pregnant women should moderate their intake of caffeine to 200mg per day from all sources.3

References

1. Pelchovitz, D. et al. Caffeine and Cardiac Arrhythmias: A Review of the Evidence. American Journal of Medicine. doi:10.1016/j.amjmed.2010.10.017

2. The British Heart Foundation. http://www.bhf.org.uk/publications/view-publication.aspx?ps=1000767 . Accessed April 2011

3. NHS Choices, http://www.nhs.uk/Planners/pregnancycareplanner/pages/Healthinpregnancyhome.aspx . Accessed April 2011

February 2011: New Data Show that Coffee Consumption May Have Beneficial Effects on All-Cause Mortality

A new study published in the European Journal of Epidemiology shows that coffee consumption may be associated with a reduction in all cause mortality and is associated with no increased risk of total cancer mortality.1 This large-scale cohort study looked at 97,753 Japanese men and women and found that all-cause mortality decreased with increasing coffee consumption in both men and women.

In addition, researchers found no association between coffee consumption and cancer mortality in men, and a weak inverse association was found in women.1This data builds on previous data in the area which has suggested that coffee consumption is inversely associated with cancer of the liver, kidney and breast.2,3,4,5

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “This data adds to the overwhelming weight of scientific research which demonstrates that moderate coffee consumption of 4-5 cups per day is safe and may be associated with some health benefits. Encouragingly, this research builds on previous research which has suggested an inverse association between coffee consumption and all-cause mortality.6,7Whilst more research is required to determine the mechanism for the effects seen in this study, the results are encouraging.”

As advised by the NHS, pregnant women should moderate their intake of caffeine to 200mg per day from all sources.8

References

1. Tamakoshi, A. et al. Effect of coffee consumption on all-cause and total cancer mortality: findings from the JACC study. European Journal of Epidemiology. DOI 10.1007/s10654-011-9548-7

2. Inoue M, Yoshimi I, Sobue T, Tsugane S, The JPHC StudyGroup. Influence of coffee drinking on subsequent risk of hepatocellular carcinoma: A prospective study in Japan. J Natl Cancer Inst. 2005;97:293–300

3. Kurozawa Y, Ogimoto I, Shibata A, et al. Coffee and risk of death from hepatocellular carcinoma in a large cohort study in Japan. Br J Cancer. 2005;93:607–10

4. Lee JE, Hunter DJ, Spiegelman D, et al. Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies. Int J Cancer. 2007;121:2246–53

5. Vatten LJ, Solvoll K, Løken EB. Coffee consumption and the risk of breast cancer. A prospective study of 14, 593 Norwegian women. Br J Cancer. 1990;62:267–70

6. Iwai N, Ohshiro H, Kurozawa Y, et al. Relationship between coffee and green tea consumption and all-cause mortality in a cohort of a rural Japanese population. Journal of Epidemiology 2002;12:191–8

7. Happonen P, La¨a¨ra¨ E, Hiltunen L, Luukinen H. Coffee consumption and mortality in a 14-year follow-up of an elderly northern Finnish population. Br J Nutr. 2008;99:1354–61

8. NHS Choices, http://www.nhs.uk/Planners/pregnancycareplanner/pages/Healthinpregnancyhome.aspx

November 2010: New Data Shows that Coffee Consumption May be Associated with a Lower Risk of Heart Failure in Women

A prospective cohort study published in the British Medical Journal demonstrates that coffee consumption may be associated with a reduced risk of heart failure in women.1Analysis of data from a cohort of 59,490 Finnish men and women (28,837 men and 30,653 women) aged 25-74 years old, showed an inverse relationship between moderate coffee consumption and heart failure in women. The results also showed that there was no increased risk of heart failure in those men who participated in the study.1

These new findings are particularly important as:

· Heart failure has become a major and growing health problem across all countries in the world, in the UK there are 63,000 new cases per year2

· Although the use of medication has reduced the re-hospitalisation rates and mortality from heart failure, it is still one of the leading causes of hospitalisation3

· Mortality of heart failure patients has remained substantial, with approximately one-quarter of patients dying within one year and half within five years of diagnoses – it is important that lifestyle factors contributing to risk of heart failure are taken into consideration.1

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “This study adds further support to the already overwhelming weight of evidence which demonstrates that coffee consumed in moderation- that is four to five cups per day, is safe and may even confer certain health benefits. The scientific evidence concludes that moderate coffee consumption does not significantly affect peoples’ risk of coronary heart disease, or their risk of stroke. Indeed recent research suggests that coffee may even have a protective effect.4 Further research to determine the mechanism of action is required, however the results are very encouraging.

This study builds on important research from Lopez Garcia et al, a study recently published in the Journal of the American Heart Association4which demonstrated that moderate coffee consumption does not significantly affect women’s risk of stroke, and may even have a protective effect.4

As advised by the Food Standards Agency guidelines, pregnant women should moderate their intake of caffeine to 200mg per day from all sources.5

References

1 Wang, Y., et al Coffee consumption and the risk of heart failure in Finnish men and women , Heart BMJ DOI:10.1136/hrt.2010.206045

2 Heart Stats http://www.heartstats.org/

3 British Heart Foundation http://www.bhf.org.uk/

4 Lopez-Garcia E., et al. Circulation – Journal of the American Heart Association, 2009 (available online: http://circ.ahajournals.org)

5 Food Standards Agency – http://www.eatwell.gov.uk/agesandstages/pregnancy/whenyrpregnant/

October 2010: Defrothing the Coffee Myths – Extensive New Data Review Shows that Coffee Consumption is Associated with a Number of Beneficial Health Effects

A detailed literature review of a number of recent scientific studies has been published in Nutrition1 and concludes that moderate amounts of caffeine may have a number of beneficial effects upon alertness, cognitive function and physical performance.

Extensive analysis of recent published research has confirmed that caffeine consumption may be associated with such benefits as increasing mental energy and cognitive functionwhich can produce increases in the functional capacity to engage in cognitively demanding tasks. In addition this review has also suggested that caffeine elevates mood and relieves anxiety.

The review has also suggested that caffeine consumption may be associated with:

1. Increasing resting energy expenditure

2. Increasing endurance and enhancing physical performance

3. Increasing neuromuscular coordination

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “This study adds further support to the already overwhelming weight of evidence which demonstrates that coffee consumed in moderation- that is four to five cups per day, is safe and may even confer certain health benefits . This extensive review builds on sound research in this area of cognitive function and physical performance which has demonstrated that moderate coffee consumption may increases levels of physical and mental alertness and performance2-8.”

As advised by the Food Standards Agency guidelines, pregnant women should moderate their intake of caffeine to 200mg per day from all sources9.

References

1. Glade, M., Caffeine – Not just a stimulant, Nutrition 26 (2010) 932-938

2. Smith, Human Psychopharmacology Clinical and Experimental; 20: 441-445, 2005

3. Dorea et al, British Journal of Nutrition; 93:773-782, 2005

4. Paluska, Current Sports Medicine Reports, 2, 213-219, 2003

5. Graham , Sports Medicine, 31, 785-807, 2001

6. Graham , Canadian Journal of Applied Physiology, 26 (Suppl.): S103-S119, 2001

7. Nehlig and Debry. International Journal of Sports Medicine, 15, 215-223, 1994

8. Dodd et al. Sports Medicine, 15, 14-23, 1993

Food Standards Agency – http://www.eatwell.gov.uk/agesandstages/pregnancy/whenyrpregnant/

September 2010: New Data Show that Coffee Consumption May be Associated with Reduced Risk of Brain Tumour

A new study published in the American Journal of Clinical Nutrition shows that daily coffee consumption was associated with a lower risk of glioma or meningioma1, types of tumour that start in the brain or spine. These findings are of interest as glioma is the most common type of primary brain tumour2

Michaud et al‘s analysis of the European Prospective Investigation into Cancer (EPIC) cohort of 521,448 participants demonstrated that there was an inverse association between coffee or tea on the development of either glioma or meningioma1.

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “This study builds on the extensive evidence which shows that moderate coffee consumption of four to five cups per day is safe and may be associated with certain health benefits . Pregnant women should follow the Food Standards Agency’s advice and limit their caffeine consumption to 200mg per day from all sources. Whilst more research is required to confirm coffee’s role in reducing an individual’s risk of brain tumour, these results are encouraging.

References

1. Michaud, D. et al, Coffee and tea intake and the risk of brain tumours in the European Prospective Investigation into Cancer and Nutrition cohort study. American Journal of Clinical Nutrition, doi: 10.3945/ajcn.2010.29876

2. NICE technology appraisal guidance 121 www.nice.org.uk

June 2010 – New Data Show that Coffee May Protect Against Head and Neck Cancers

A new study published in Cancer Epidemiology, Biomarkers & Prevention suggest those who drink four or more cups of coffee per day may have a 39% decreased risk of oral cavity and pharynx cancers combined, compared with non-coffee drinkers.1

This review from a pooled-analysis of nine studies collected by the International Head and Neck Cancer Epidemiology (INHANCE) consortium revealed that the association is more reliable amongst those who are frequent, regular coffee drinkers . Tea consumption was not associated with head and neck risk.1

These results are important as:

· Approximately 7800 people in the UK are diagnosed with head and neck cancers each year2

· The mortality rate for head and neck cancers is just over 50%3

· Mouth cancer kills one person every 3 hours in the UK because of late detection3

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “The impact of coffee consumption upon the development of head and neck cancer has not been widely studied, however this study shows that moderate coffee consumption of 4-5 cups of coffee per day may be associated with a reduced incidence of the cancer may in fact play a role in prevention. Additional research is needed to determine the mechanisms of action, but the data is very encouraging and builds on research which has demonstrated that moderate coffee consumption does not increase the risk of cancer of the kidney or pancreas 4

As advised by the Food Standards Agency guidelines, pregnant women should moderate their intake of caffeine to 200mg per day from all sources5.

References

1. Types of Head and Neck Cancer, Macmillan http://www.macmillan.org.uk/Cancerinformation…

2. Patient’s Guide, Mouth Cancer Foundation http://www.rdoc.org.uk/patientguide.html

3. Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective – a report from the World Cancer Research Fund: http://www.dietandcancerreport.org/

4. Food Standards Agency, http://www.food.gov.uk/news/newsarchive/2008/nov/caffeinenov08

May 2010 – New Data Shows that Coffee Consumption May be Associated with a Statistically Significant Lower Risk of Parkinson’s Disease

A meta-analysis of observational studies published in the Journal of Alzheimer’s Disease in 2010 demonstrates that coffee consumption may be associated with a 25% reduction in the risk of Parkinson’s disease.Analysis of data from 25 cohort, nested case-control and cross sectional studies, showed an inverse relationship between caffeine consumption and the risk of development of Parkinson’s disease.

The results of the study also indicate an inverse association, with higher intakes of caffeine being associated with a lower risk of Parkinson’s disease1.

Parkinson’s disease is the second most common neurodegenerative disease with an estimated world-wide prevalence of 0.5 to 4% among the elderly. It has long been thought that coffee consumption can help to prevent the onset of Parkinson’s disease, and studies conducted throughout the world from 1968 up until the present day have demonstrated that coffee consumption is associated with a lower risk of Parkinson’s disease1.

These findings are particularly important as:

· One person in every 500 has Parkinson’s disease- that’s 120,000 people in the UK2

· There is currently no cure for Parkinson’s disease, and scientists don’t yet know why people develop the condition2

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “This study adds further support to the already overwhelming weight of evidence which demonstrates that coffee consumed in moderation- that is four to five cups per day, is safe and may confer certain health benefits . This evaluation builds on sound research in this area which has demonstrated that moderate coffee consumption may protect against the onset of Parkinson’s disease3,4,5,6,7,8. Further research to determine the mechanism of action is required, however the results are very encouraging .”

References

1 Journal of Alzheimer’s Disease 20 (1020) S221-S238 http://www.j-alz.com/issues/caffeine.html

2 Parkinsons.org http://www.parkinsons.org.uk/about_parkinsons/what_is_parkinsons.aspx

3 Eskelinen et al, Journal of Alzheimer’s Disease, Volume 16, 2009 Hernan et al, Annals of Neurology, Volume 52, 2002

4 Ascherio et al, Annals of Neurology, Volume 50, 2001

5 Ross et al, Journal of the American Medical Association, Volume 283, 2000

6 Ascherio et al, American Journal of Epidemiology, Volume 160, 2003

7 Maia and De Mendonca, European Journal of Neurology, Volume 9, 2002

8 Lindsay et al, American Journal of Epidemiology, Volume 156, 2002

9 Food Standards Agency, http://www.food.gov.uk/news/newsarchive/2008/nov/caffeinenov08

December 2009 – New Data Shows that Coffee Consumption May be Associated with a Lower Risk of Coronary Heart Disease in Women

A meta-analysis of a number of cohorts studies published in the International Journal of Cardiology1 demonstrates that habitual coffee consumption may be associated with a lower risk of coronary heart disease (CHD) in women.

Analysis of data from 21 cohort studies showed that moderate coffee consumption (of up to four cups of coffee per day) were associated with a 18% reduction in risk of CHD in women 1 . The investigators note that such an effect was unlikely to be caused by chance.

These new findings are particularly important as:

  • Coronary heart disease is the UK’s biggest killer, with one in every six women dying from the disease2
  • In women, cardiovascular disease (CVD), including CHD and stroke, accounts for more deaths across all ages than cancer, diabetes or respiratory disorders3

Dr Euan Paul, Executive Director of the British Coffee Association, commented, “ A large number of studies have addressed coffee consumption and the risk of CHD, but have not provided definitive results. This study demonstrates that not only does coffee consumption not increase the long-term risk of CHD, but that moderate coffee consumption may actually reduce the risk of the disease in women. These data further demonstrate that moderate coffee consumption of four to five cups per day is safe and may even confer certain health benefits such as reducing the risk of developing Alzheimer’s disease, Parkinson’s disease, type 2 diabetes and, as shown in this study, may even reduce risk of CHD in women. As advised by the Food Standards Agency guidelines, pregnant women should moderate their intake of caffeine to 200mg per day from all sources .”

It is also worth noting that earlier in the year, data published in Circulation also suggested that coffee consumption may be associated with a 19% reduction in risk of stroke in women4.

References

1. Wu, J. Coffee consumption and risk of coronary heart diseases: A meta-analysis of 21 prospective cohort studies. International Journal of Cardiology 2009 137:216-225

2. Coronary Heart Disease, NHS Choices – http://www.nhs.uk/conditions/Coronary-heart-disease/Pages/Introduction.aspx Accessed December 2009

3. Deaths caused by cause, sex, age, 2007, United Kingdom, British Heart Foundation http://www.heartstats.org/datapage.asp?id=713 Accessed December 2009

4. Lopez-Garcia, E., et al Circulation – Journal of the American Heart Association , 2009 (available online: http://circ.ahajournals.org )